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During metabolism the most uncertain point is how GABA enters the mitochondrion

Effect of Vitamin E and Memantine on Functional Decline in Alzheimer Disease

Regardless of rates of GSH consumption, which are likely to increase with secondary infections, our finding that the lower erythrocyte GSH concentration of asymptomatic HIV-infected individuals is associated with lower rates of synthesis of the tripeptide demonstrates conclusively that impaired GSH synthesis contributes to the GSH deficiency associated with HIV infection